MHC-HM429F-100μg / 询价
MHC-HM429F-500μg / 询价
MHC-HM429F-500μgx2 / 询价
表达区间及表达系统(Source)
|
Recombinant FITC-Labeled Human HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. It contains Gly25-Thr305 (HLA-A*11:01), Ile21-Met119 (B2M) and VVVGAGGVGK peptide.[Accession | AAV53343.1(HLA-A*11:01)&P61769(B2M)&VVVGAGGVGK] |
分子量大小(Molecular Weight)
|
The protein has a predicted MW of 50.30 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Tris-Bis PAGE result. |
波长(Wavelength)
|
Excitation Wavelength: 490 nm Emission Wavelength: 520 nm |
内毒素(Endotoxin)
|
Less than 1EU per μg by the LAL method. |
纯度(Purity)
|
> 95% as determined by Tris-Bis PAGE |
制剂(Formulation)
|
Supplied as 0.22μm filtered solution in PBS (pH 7.4). |
存储(Storage)
|
Valid for 12 months from date of receipt when stored at -80°C. |
Recombinant FITC-Labeled Human HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. It contains Gly25-Thr305 (HLA-A*11:01), Ile21-Met119 (B2M) and VVVGAGGVGK peptide.[Accession | AAV53343.1(HLA-A*11:01)&P61769(B2M)&VVVGAGGVGK]
The protein has a predicted MW of 50.30 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Tris-Bis PAGE result.
Excitation Wavelength: 490 nm
Emission Wavelength: 520 nm
Less than 1EU per μg by the LAL method.
> 95% as determined by Tris-Bis PAGE
> 95% as determined by HPLC
Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
MHC; KRAS; K-Ras 2; KRAS2; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KRAS1; KRAS2; NS; NS3; RASK2; GTPase Kras; KI-RAS; RALD
(1) Wu HZ, Xiao JQ, Xiao SS, Cheng Y. KRAS: A Promising Therapeutic Target for Cancer Treatment. Curr Top Med Chem. 2019;19(23):2081-2097. doi: 10.2174/1568026619666190905164144. PMID: 31486755.
MHC-HM429F-100μg / 询价
MHC-HM429F-500μg / 询价
MHC-HM429F-500μgx2 / 询价
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